Bowers Vers 50 is the silencer if you want to effectively suppress your .50 Beowulf (or other big bore caliber - like the .45-70).
The Bowers VERS 50 is a .50 caliber high-efficiency suppressor. The Vers 50 was designed for use with calibers .510 and smaller up to 2200 fps velocity. It's also suitable for slower rounds that will fit through the bore, like: Full Power, .50 Beowulf, .50 Alaskan, .458 Socom, .50 AE, 45/70 loadings, and .510 Beowulf.